Millennium (MLNM posted a fourth-quarter net loss of $67 million, or 30 cents per share, compared with a net loss of $37.5 million, or 18 cents per share, in the 2000 fourth quarter.
Excluding amortization charges and certain other expenses, Millennium said its fourth-quarter loss was $50.4 million, or 23 cents per share. The Cambridge, Mass.-based company had been expected to post a loss of 19 cents per share, according to the average estimate of analysts polled by Thomson Financial/First Call.
Millennium said revenue from its research partnerships slipped in the fourth quarter to $54.6 million from $58.7 million in the year-ago quarter.
Millennium, which is developing treatments for cancer and obesity, said research and development expenses jumped to $114.6 million from $77.8 million in the year-ago quarter.
For 2002, Millennium said it expects to post a loss in the range of $175 million to $200 million. Total revenue for this year is expected to be $400 million compared with $246.2 million for 2001, the company said.
As of Dec. 31, Millennium reported having about $1.5 billion in cash, cash equivalents and marketable securities.
Millennium in December agreed to buy Cor Therapeutics in an all-stock deal valued at $2 billion. Millennium said it was making the buy to get access to Cor's Integrilin drug, used to prevent blood clotting and treat angina, a painful heart condition.
Millennium said Tuesday it expects sales of Integrilin to rise 30 percent to $300 million in 2002. Of that $300 million total, Millennium said it expects to record about $150 million in revenue.
Millennium said it expects its acquisition of Cor to close on Feb.12.
Ahead of the announcement, which was released after the close of regular trading, Millennium shares edged down 17 cents to $20.23 while shares of Cor lost 28 cents to $19.79.
Ted Griffith is a reporter for CBS.MarketWatch.com